HCV RNA by PCR used for screening Of all blood components since Sep., 1999

Aim of HCV RNA by PCR because Mandatory blood viral screening tests though very effective, yet doesn't offer absolute blood safety ( residual risk) .

Among causes of post transfusion viral infections are:

  1. Window period, which means that during this time the donor's blood become infective and the conventional tests are still negative.
  2. Viral variants.
Molecular biology tests like HCV RNA by PCR technique reduces the residual risk due to the above mentioned causes to almost zero.



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