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Component /Product

Composition

Volume

Indications

Acute complicatios

Delayed complication

Whole blood

RBC [ Approx. Hct 40% plasma ; WBC and platelets

About
450 ml

Increase both red cell mass and plasma volume [WBC & Platelets are not functional ; plasma deficient in labile clotting factors V,VIII]

Hemolytic febrile , allergic and anaphylaxis

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection

Red Blood cells

RBC [ Approx. Hct 75%] reduced plasma ; WBC and platelets

250 ml

Increase red cell mass in symptomatic anemia [ WBC and platelets not functional]

Hemolytic febrile , allergic and anaphylaxis

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection

Red Blood cells , Additive soultion

RBC [ Approx. Hct 60%] reduced plasma ; WBC and platelets ,
100 ml of additive solutions

330 ml

Increase red cell mass in symptomatic anemia [ WBC and platelets not functional]

Hemolytic febrile , allergic and anaphylaxis

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection

Leukocyte Reduced RBC [prepared by filtration or centrifugation]

RBC [Approx. HCT 75%]; few platelets; minimal plasma; <5X106 to <5X108 WBC

About
220 ml

Increase red cell mass ; prevent febrile reaction due to Leukocyte antibodies ; decrease the possibility of immunization to Leukocyte or HLA antigens

Hemolytic febrile , allergic and anaphylaxis

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection

Washed RBC

RBC [ Approx. Hct 75%] <5X108 WBC ; no platelets ; no plasma

About
220 ml

Increase red cell mass ; reduce risk of allergic reactions to plasma proteins

Hemolytic and febrile

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection

RBC frozen /deglycerolized

RBC [ Approx. Hct 75%] <5X108 WBC ; no platelets ; no plasma

180 ml

Increase red cell mass ; reduce risk of febrile or allergic reaction used

Hemolytic

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection

Platelets (random donor)

Platelets [ >0.5X1011 /unit];RBC; plasma

50 ml

Bleeding due to thrombasthenia or thrombocy topenia

Febrile ,allergic and anaphylaxis

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection

Platelets a pheresis

Platelets [>3X1011/unit] RBC; plasma

About
250 ml

Same as Platelets ; sometimes HLA matched

Same as Platelets

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection

Granulocytes a pheresis

Granulocytes , lymphocytes ; platelets [ <1X1010 PMN/unit ; > 2X1010 platelets/unit] RBC

220 ml

provide Granulocytes for selected patients

Hemolytic febrile and allergic

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection

Fresh frozen plasma FFP

Plasma ; all coagulation factors ; complement (no platelets)

About
180 ml

Treatment of some coagulation disorders

Allergic and anaphylaxis, rarely hemolytic

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection

Cryoprecipitated AHF

Fibrinogen ; F VIII ; F XIII ; vWF and fibronectin

About
40 ml

Hemophilia A ; vW disease ; Fibrinogen deficiency and F XIII deficiency

Allergic and anaphylaxis

delayed hemolytic reaction - post transfusion purpura - transfusion transmitted  infection